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The normal sequence of action of these components of the hormonal hierarchy is:


A) adrenal cortex \rightarrow hypothalamus \rightarrow anterior pituitary.
B) anterior pituitary \rightarrow adrenal cortex \rightarrow hypothalamus.
C) anterior pituitary \rightarrow hypothalamus \rightarrow adrenal cortex.
D) hypothalamus \rightarrow adrenal cortex \rightarrow anterior pituitary.
E) hypothalamus \rightarrow anterior pituitary \rightarrow adrenal cortex.

F) All of the above
G) C) and E)

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Describe five possible fates of amino acids arriving in the liver after intestinal uptake.

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Possible answers include:
(1)synthesis ...

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Provide some distinguishing characteristics between peptide hormones and thyroid hormones.

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Although both peptide hormones and thyro...

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An example of a steroid hormone is:


A) epinephrine.
B) retinoic acid.
C) testosterone.
D) thromboxane.
E) thyroxine.

F) C) and D)
G) A) and B)

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Describe five possible fates for glucose 6-phosphate in the liver.

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Possible answers include:
(1)conversion...

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Some hormones trigger very rapid responses,whereas for others the response takes much longer to develop.What generalization about the mechanisms of action of these two types of hormones can explain the differences in response times?

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Fast-acting hormones affect th...

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What is leptin? How does it function in the long-term maintenance of body mass?

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Leptin is a small polypeptide that is pr...

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The tropic hormones (such as thyrotropin,somatotropin,and luteinizing hormone) are produced and released by the:


A) anterior pituitary.
B) hypothalamus.
C) ovaries.
D) pancreas.
E) posterior pituitary.

F) C) and D)
G) D) and E)

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Which one of the following statements is true?


A) The brain prefers glucose as an energy source,but can use ketone bodies.
B) Muscle cannot use fatty acids as an energy source.
C) In a well-fed human,about equal amounts of energy are stored as glycogen and as triacylglycerol.
D) Fatty acids cannot be used as an energy source in humans because humans lack the enzymes of the glyoxylate cycle.
E) Amino acids are a preferable energy source over fatty acids.

F) A) and B)
G) C) and E)

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A major difference between white adipose tissue and brown adipose tissue is that only:


A) white adipose tissue stores fatty acids as triacylglycerols.
B) brown adipose tissue degrades fatty acids via the citric acid cycle.
C) brown adipose tissue contains thermogenin.
D) white adipose tissue contains adipocytes.
E) white adipose tissue responds to hormone signals.

F) B) and C)
G) A) and E)

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Provide some distinguishing characteristics between eicosanoids and hormones such as epinephrine.

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Eicosanoids are paracrine hormones deriv...

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The hormone leptin appetite;insulin appetite.


A) increases;increases
B) increases;decreases
C) decreases;increases
D) decreases;decreases
E) has no effect on;has no effect on

F) C) and D)
G) B) and E)

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Briefly explain the role of phosphocreatine in muscle.

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During maximal muscle activity,muscle ce...

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Which of the following hormones stimulates appetite?


A) Grehlin
B) Insulin
C) Adiponectin
D) Both A and B
E) Both A and C

F) A) and B)
G) A) and C)

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Briefly describe the "lipid burden" hypothesis that explains the development of type 2 diabetes.

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Excessive caloric intake by obese individuals causes adipocytes to become completely filled with triacyclglycerols,unable to take up and store any additional fatty acids.These lipid-filled adipocytes release signals that attract macrophages that invade the fat tissue and trigger an inflammatory response.The inflammatory response further impairs uptake of fatty acids and leads to even higher levels of free fatty acids in the bloodstream.The excess free fatty acids are taken up by the liver and muscle cells.The fatty acids are then converted to triacylglycerols and stored as lipid droplets.These lipid droplets are toxic to these cells,leading to eventual insulin resistance through a variety of mechanisms.

The Cori cycle is:


A) the conversion of lactate to pyruvate in skeletal muscle to drive glycogen synthesis.
B) the interconversion between glycogen and glucose l-phosphate.
C) the production of lactate from glucose in peripheral tissues with the resynthesis of glucose from lactate in liver.
D) the synthesis of alanine from pyruvate in skeletal muscle and the synthesis of pyruvate from alanine in liver.
E) the synthesis of urea in liver and degradation of urea to carbon dioxide and ammonia by bacteria in the gut.

F) None of the above
G) D) and E)

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C

In its role in the hormonal hierarchy,the hypothalamus produces and releases:


A) epinephrine.
B) insulin.
C) progesterone.
D) releasing factors.
E) thyroxine.

F) A) and B)
G) A) and C)

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Name five general classes of hormones and give an example of each.

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(1) Peptide (e.g., insulin, glucagon);
...

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Epinephrine is an example of a(n) ____________ hormone.


A) catecholamine
B) eicosanoid
C) paracrine
D) peptide
E) steroid

F) All of the above
G) A) and B)

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The peptide hormone adiponectin,produced in adipose tissue,circulates in the blood and:


A) enhances fatty acid synthesis in liver cells.
B) increases the rate of β\beta -oxidation of fatty acids in muscle cells.
C) inhibits glucose uptake and catabolism in muscle and liver cells.
D) reduces the transport of fatty acids into muscle cells.
E) stimulates gluconeogenesis in liver cells.

F) A) and C)
G) All of the above

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B

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